13590-42-6 H-Asp(OBzl)-NCA

Su'esu'ega fa'aolaola:
I le peptide synthesis, H-Asp(OBzl) -NCA e avea o se poloka fale taua mo le tuʻufaʻatasia o filifili peptide o loʻo i ai faʻasologa o vailaʻau aspartic.
O lona kulupu ester benzyl e galue o se vaega puipuia, e mafai ai mo le faʻaofiina o suiga faʻapitoa o vailaʻau i le taimi o le peptide chain synthesis, lea e mafai ona aveese i lalo o tulaga talafeagai e maua ai le faʻasologa o le aspartic acid e manaʻomia.
I suʻesuʻega o suʻesuʻega o le protein poʻo le peptide, H-Asp(OBzl) -NCA e mafai ona faʻaaogaina e faʻafeiloaʻi ai suiga faʻapitoa o vailaʻau e suʻesuʻe ai pe faʻafefea ona aʻafia e nei suiga le gaioiga o meaola poʻo fegalegaleaiga ma isi molelaʻau o le porotini poʻo le peptide.
Su'esu'eina o Vailaau Fa'asaina:
H-Asp(OBzl) -NCA e mafai ona avea o se mea faʻapipiʻi muamua poʻo se vaeluaga mo molelaʻau vailaʻau, faʻatagaina mo le faʻaofiina o fausaga vailaʻau faʻapitoa i le taimi o le mamanu vailaʻau e maua ai sui tauva faʻatau ma gaioiga faʻaola.
E ala i faʻalavelave faʻatasi ma isi vaega vailaʻau poʻo meaola ola olaola, e mafai ona faʻafaigofie le tuʻufaʻatasia o vailaʻau faʻavae peptide poʻo heterocyclic faʻatasi ma aʻafiaga faʻapitoa.
I faiga su'esu'e vaila'au, H-Asp(OBzl) -NCA e mafai fo'i ona fa'aogaina i su'esu'ega maualuga ma su'esu'ega fa'aolaola e iloilo ai gaioiga o fa'asologa o peptide eseese po'o sui tauva.
Alamanuia tau vailaau:
I totonu o fale gaosi oloa, H-Asp(OBzl) -NCA o loʻo avea o se mea mataʻutia poʻo se vaeluaga mo le gaosiga o vailaʻau peptide malosi.
E ala i faʻamaʻi faʻatasi ma isi amino acids poʻo vaega o fualaau faasaina, e mafai ona faafaigofieina le tuʻufaʻatasia o vailaʻau peptide faʻatasi ai ma gaioiga faʻapitoa, e pei o vailaau faʻamaʻi, hormones, inhibitors enzyme, ma isi mea.
O le vaega o le benzyl ester o loʻo iai i lona fausaga e puipuia ai le carboxylic acid o le aspartic acid, e fesoasoani i le mautu ma le gaioiga o le filifili peptide i le taimi o le faʻasologa.