Saina 40216-83-9 H-Hyp-Ome·HCl Gaosiga ma Falegaosi |Jiayinglai

40216-83-9 H-Hyp-Ome·HCl

Fa'amatalaga Puupuu:

Fa'aaliga	Pa'u pa'epa'e
MF	C6H12ClNO3
MW	181.62
Mama	98+

Auina imeli ia matou

Fa'amatalaga Oloa

Tulaga felauaiga
E ono iai ile vevela masani

Fautuaina auala felauaiga
I le ea I le laueleele I le sami

Tulaga teuina:
Taofi i se nofoaga pogisa, Inert atemosifia, potu vevela

Ola fa'asa
E tusa ma le 2 tausaga

Fa'atauga aupito maualalo:
1kg (fa'atalanoaga)

Fa'ailoga:COA, mea liusuavai, Ta'amilosaga Fa'apitoa [α]_D²⁰

Matou te lafoina soʻo se faʻamatalaga e te manaʻo ai.E mafai ona e vaʻai i faʻamatalaga muamua e fai ma faʻamatalaga.

Mo oloa faʻapitoa, matou te lafoina faʻamatalaga fou pe a uma ona oʻo mai.

Synonyms

H-HYP-OMEHCL;
HL-HYP-OMEHCL;
HYDROXYPROLINE-OMEHCL;
(2S,4R) -trans-4-hydroxy-L-prolinemethylesterhydrochloride;
4-hydroxy-2-pyrrolidinecarboxylicacidmethylesterhydrochloride;
L-4-HYDROXYPROLINEMETHYLESTERHYDROCHLORIDE;
L-4-HYDROXYPROLINEMETHYLESTERHYDROCHLORIDESALT;
L-4-TRANS-HYDROXYPROLINEMETHYLESTERHYDROCHLORIDE

totonu afifiina

E masani ona faʻaaogaina mo le faʻapipiʻiina o le pauta.E fa'alagolago i manaoga o tagata fa'atau.O le mea lea, taʻu mai ia i matou lau manaʻoga aʻo leʻi faʻapipiʻiina pe a iai ni au talosaga faʻapitoa.

afifiina i fafo

1kg i le 25kg O le afifiina i fafo e faigata.Ma e faigata ona tipi ma faʻaleagaina.E mafai ona puipuia lelei au oloa.

Talosaga

Fa'aoga: H-Hyp-OMe·HCl o lo'o avea ma feso'ota'iga ADC (antibody-drug conjugate) e le mafai ona fa'aogaina mo le tu'ufa'atasiga o ADC.ADCs, e aofia ai se antibody ma se cytotoxin e feso'ota'i e ala i se feso'ota'iga ADC, e mafai ai ona fa'ao'o sa'o o cytotoxins i sela fa'atatau, ma togafitia ai fa'ama'i fa'apitoa.E le gata i lea, o le H-Hyp-OMe·HCl o se PROTAC (protein degradation targeting chimera) linker e faʻavae i luga o filifili alkyl, faʻaaogaina i le tuʻufaʻatasia o PROTACs.PROTACs, o loʻo i ai ni liga maʻoti e lua e fesoʻotaʻi e se soʻotaga, faʻaogaina le telefoni feaveaʻi ubiquitin-proteasome system e filifili faʻaleagaina ai polotini taulaʻi.

Meatotino: H-Hyp-OMe·HCl ose pa'epa'e po'o sina samasama pa'u amorphous e mafai ona solu i solu e pei o vai, methanol, ma ethanol.E faʻaalia lelei le mautu ma le biocompatibility, faʻatumauina lona gaioiga ma le mautu i lalo o tulaga faʻaletino.

I le aotelega, o le H-Hyp-OMe·HCl o loʻo i ai se sao taua i le tuʻufaʻatasia o ADCs ma PROTACs e avea o se mea faʻapitoa faʻaola kemikolo ma mea faigaluega faʻamalosi.E maua ai auala fou ma auala mo togafitiga o faʻamaʻi.A'o fa'aauau su'esu'ega ma fa'atupuina fa'atekonolosi, e fa'amoemoe e fa'alautele le fa'aogaina o fa'amoemoega ole H-Hyp-OMe·HCl.

oloa fa'atatau

L-Hyp-OH	HL-Hyp-Ome·HCl
HL-Hyp-Oet.HCl	L-Hyp-Obzl.Hcl
Boc-L-Hyp-OH	Boc-L-Hyp-Ome
Fmoc-L-Hyp-Ome	Boc-L-Hyp-oet
Fmoc-L-Hyp-OH	Fmoc-L-Hyp(tbu)-OH
Cbz-L-Hyp-OH	Cbz-L-Hyp-OMe

Fa'asilisili

1. Matou te tuʻuina atu faʻasalalauga oloa e te manaʻomia.
2. Tulaga maualuga & tau fa'atauva e mafai ona tu'uina atu.
3. Matou te folafola atu se vasega atoa o auaunaga tulitatao mo oe.
4. E mafai ona tu'uina atu fesili a le tagata fa'atau oloa ma pepa fa'atekinisi pe a mana'omia pe a uma ona fa'amalieina se aofa'i.
5. Au'aunaga sili pe a uma ona fa'atau atu po'o fa'amaoniga: So'o se tasi o au fesili o le a foia i se taimi vave e mafai ai.
6. Fa'atauva'a oloa fa'atauva'a ma fa'atau atu i fafo i le tele o tausaga ta'itasi.
7. Fa'ata'ita'iga fua e ofoina atu e siaki ai le lelei a'o le'i totogiina.

Muamua: 33208-99-0 L-Ala-NH2.HCl

Sosoo ai: 7362-93-8 H-Asp-OBzl

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